Characteristics of CdLs
The features of this disorder vary widely among affected individuals and range from relatively mild to severe.
Cornelia de Lange syndrome is characterized by:
Facial features includes:
Many affected individuals also have behavior problems similar to autism, a developmental condition that affects communication and social interaction.
There are some conditions, which makes self-injurious behavior more likely to occur: pain, discomfort, frustration or dismay. The typical young person with CdLS may be described as hypersensitive and dysrhythmic.
Another sypmtom of CdLS can include excessive body hair know as hirsutism, an unusually small head (microcephaly), hearing loss, short stature, and problems with the digestive tract. Some children are born with a cleft pallet. Seizures, heart defects, eye problems, and skeletal abnormalities also have been reported in people with this condition.
Cornelia de Lange syndrome is characterized by:
- Slow growth before and after birth
- Intellectual disability that is usually severe to profound
- Skeletal abnormalities involving the arms and hands
- Distinctive facial features.
Facial features includes:
- Arched eyebrows that often grow together in the middle
- Long eyelashes
- Low-set ears
- Small, widely spaced teeth
- A small, upturned nose.
- Small hands
- incurved fifth finger
- Proximally placed thumb
- Limited elbow movement
- Shortened limbs
- Club foot
Many affected individuals also have behavior problems similar to autism, a developmental condition that affects communication and social interaction.
There are some conditions, which makes self-injurious behavior more likely to occur: pain, discomfort, frustration or dismay. The typical young person with CdLS may be described as hypersensitive and dysrhythmic.
- May be hypersensitive in that they may have strong reactions to ordinary stimuli and these reactions may continue long after the stimulus is gone.
- They may be dysrhythmic, which means having irregular patterns of behavior in the areas of eating, sleeping and emotional response.
- May also be prone to behavioral problems such as hyperactivity, short attention span, and oppositional or repetitive behavior.
Another sypmtom of CdLS can include excessive body hair know as hirsutism, an unusually small head (microcephaly), hearing loss, short stature, and problems with the digestive tract. Some children are born with a cleft pallet. Seizures, heart defects, eye problems, and skeletal abnormalities also have been reported in people with this condition.